大规模研究揭示纤维肌痛的遗传基础

The mysterious pain disorder fibromyalgia may have some surprising genetic roots. An analysis of 2.5 million people suggests the disorder is neurological in nature, scientists report in Nature Medicine. The genetics study is the latest — and largest — to try and get a grasp on a long-debated condition. The work establishes a biological basis for fibromyalgia, which was historically thought to be psychological. Evidence of the condition’s biological origins has been accumulating for years, says geneticist Michael Wainberg of the University of Toronto. “But now,” he says, “I think it’s absolutely indisputable.” Fibromyalgia affects some 4 million adults in the United States and is known for causing widespread pain and fatigue — though symptoms can look different among patients. …