空间分辨单细胞图谱揭示动物心脏的宏观演化轨迹

Shanshan Lian†, Wei Wang†, Yaoxin Liu†, Meina Lu†, Wentao Han†, Jiaxin Luo†, Xuejiao Zhang†, Yue Pang†, Yuru Li† et al. INTRODUCTION: The heart represents a key evolutionary innovation in the rise of complex animal life. Yet the cellular and molecular basis of heart diversity, its deep evolutionary origins, and the modes of convergent versus divergent evolution across phyla are largely unresolved. Addressing these fundamental questions is critical not only for understanding metazoan organ evolution but also for providing evolutionary context to human cardiac biology and disease. …