可编程的细胞蛋白工厂

Engineered immune cell precursors produce antibodies on demand in mice Richard G. James1,2 and Ting-ting Zhang1 V accines have transformed global health through their role in controlling or eradicating infec- tious diseases. For example, they can elicit B cells to produce antibodies that recognize differ- ent strains of a particular pathogen. However, conventional immunization with weakened or inactivated pathogens, or a component of the pathogen, is often diffi- cult because the relevant precursor B cells are rare and the process by which they generate antibodies with increased affinity to the pathogen’s antigens is complex and lengthy (1). …