A helper NLR channels organellar calcium to trigger plant immunity · T. Ibrahim et al.
原文开头
Tarhan Ibrahim1†, Freddie J. King1†, AmirAli Toghani2, Luyao Wang1, Saskia Jenkins1, Enoch Lok Him Yuen1, Hung-Yu Wang1,3, Cristina Vuolo1, Nick Eilmann1, Vanda Adamkova1, Khong-Sam Chia4, Baptiste Castel2, Jonathan D. G. Jones2, Philip Carella4, Chih-Hang Wu3, Jiorgos Kourelis1*, Sophien Kamoun2*, Tolga O. Bozkurt1* Upon activation, plant nucleotide-binding leucine-rich repeat (NLR) immune receptors are known to assemble into oligomeric resistosomes that insert into the plasma membrane, forming calcium (Ca2+)–permeable channels and triggering immunity. Here, we found that the RPW8-like coiled-coil NLR (CCR-NLR) N requirement gene 1 (NRG1) primarily targets organelles instead of the plasma membrane. Unlike canonical CC-NLRs, activated NRG1 accumulated at the chloroplast envelope and channeled stromal Ca2+ into the cytosol. …
摘自《科学》(Science)第392卷 第6797期 · 2026年4月30日,T. Ibrahim et al.。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。