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《科学美国人》 第334卷 第6期 · 2026年6月刊 · 中文解读

受奥泽匹克启发,科学家测试新药以延缓衰老过程中的肌肉流失

The Science of Health: Inspired by Ozempic, scientists are testing new drugs to keep you from losing muscle as you age · Lori Youmshakejian
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这篇讲什么
本文探讨了GLP-1药物如奥泽匹克和维格威在减重的同时导致肌肉流失的问题,以及制药公司正在开发的旨在保留肌肉的新疗法,如bimagrumab和SARMs。
原文开头
New Ways to Keep Muscle as You Age Ozempic, similar drugs and aging take off muscle. New therapies could retain it BY LORI YOUMSHAJEKIAN D RUGS SUCH AS WEGOVY and Ozempic can lead to pro- found weight loss, but fat isn’t the only thing that comes off. About 25 to 40 percent of the pounds shed through these treatments is lean body mass, and that includes mus- cle. This undesired effect has troubled older adults who are already worried about age-related muscle loss tied to falls and bone fractures. Preserving muscle matters for young adults as well: the more you have in your 30s, the more you will retain in your 60s. …
摘自《科学美国人》(Scientific American)第334卷 第6期 · 2026年6月刊,Lori Youmshakejian。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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