阻止自身免疫攻击

IgA nephropathy, a frequent cause of kidney failure, is underdiagnosed. New treatments mean it’s more important now to find those who will benefit By Charles Schmidt THE MAN IN HIS 50s ARRIVED at Ellie Kelepouris’s office carrying a sheaf of medical records. They contained years’ worth of labora- tory test results that showed microscopic traces of blood in his urine. Kelepouris, a nephrologist at the University of Pennsylvania’s Perelman School of Medicine, wasn’t the first kidney specialist he had consulted about the problem. “I don’t want to have blood in my urine,” the man said. “I don’t know what’s going on.” Kelepouris suspected the cause, but it took a kidney biopsy, done in 2024, to confirm it. …