十亿道尔顿超分子聚合物的精确长度与电荷分段

Precise length and charge segmentation of billion- dalton supramolecular polymers Michael D. Dore1†, Madison Strong2†, Simon A. Egner3†, Hiroaki Sai1, Kyle Gray3, Nozomu Takata1,4, Alexie Nyambi3, Zhiwei Li1, Liam C. Palmer1,5, Samuel I. Stupp1,2,3,4,5,6* Supramolecular polymers with precise micrometer- scale segments of opposite charge are challenging to synthesize as discrete assemblies in water. these systems could be used to pattern charged surfaces, interact with the membranes of cells, or form hierarchical structures. We report a living polymerization of fibrillar peptide assemblies with a central positively charged segment flanked by negative ones that can have a collective molar mass on the order of billions of daltons. …