塑造母体生理：免疫系统对生殖适应的调控

Dan Corral1* and Yasmine Belkaid2* Pregnancy is one of the most extensive physiological transitions of adult life, requiring coordinated adaptation across virtually every maternal organ to support fetal growth while preserving maternal health. Although these changes have traditionally been viewed as endocrine driven, emerging evidence identifies the immune system as an active regulator of maternal physiology. The immune system is increasingly recognized as a broad regulator of host physiology, positioning it as a key driver of maternal adaptation. In this work, we discuss how pregnancy reprograms maternal immunity to orchestrate physiological reprograming of tissues. …