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《科学》 2026年10月1日 · 中文解读

对女性健康的终身关注

A LIFELONG FOCUS ON WOMEN’S HEALTH · Y. Nusinovich et al.
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这篇讲什么
长期以来,大多数人体研究只纳入男性参与者,其结论却被假定同样适用于女性和儿童,女性健康也往往只在生育语境中被提及。如今生物医学研究已清楚表明,许多与生殖无关的疾病在不同性别间存在差异,且贯穿人的一生。性染色体、X染色体失活、妊娠与哺乳带来的免疫重塑以及卵巢在生育期之后的生物学功能,都是仍待深入理解的关键问题。
原文开头
Historically, most human studies have involved male participants, and their findings were assumed to apply to women and children as well. Meanwhile, women’s health typically came up in the context of reproduction and childbearing, if at all. However, biomedical science has come a long way over the years, and it has become increasingly clear that there are sex-dependent differences in many diseases that do not involve reproduction and that occur at all ages. Across all areas of women’s health, including both reproductive and nonreproductive conditions, much remains to be learned about the underlying biology, effects of hormones and genetics, and potential therapeutic interventions. …
摘自《科学》(Science)2026年10月1日,Y. Nusinovich et al.。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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