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《科学》 2026年10月1日 · 中文解读

美国中部的一场医学谜团:一个家族接连罹患罕见痴呆症

A medical mystery unfolds in middle America · Nancy Berlinger
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这篇讲什么
记者罗伯特·科尔克在新书《消失的家族》中记录了一个美国中西部家庭的故事:九个兄弟姐妹中有五人患上额颞叶痴呆,这种遗传性痴呆由MAPT基因的V337M突变引起。书中既穿插脑科学史,也呈现了以苏为代表的家庭照护者长达数十年的付出,揭示美国老龄化社会中照护工作的沉重代价。
原文开头
As a rare form of dementia claims one sibling after another, a journalist captures the profound costs of caregiving Nancy Berlinger Dementia is nearly always a family disease, because most dementia caregivers are family members of the person in need of care. In The Vanishing Family, journalist Robert Kolker provides an account of what dementia caregiving is like that is as breathtaking as the scientific “quest to end dementia” that the subtitle proclaims. This is Kolker’s second book about a large postwar American family with bad medical luck. In his 2020 bestseller Hidden Valley Road, six sons in a family of 12 are diagnosed with schizophrenia. …
摘自《科学》(Science)2026年10月1日,Nancy Berlinger。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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