Mitochondrial genomes on a string of pearls · J. van den Ameele and J. Prudent
原文开头
Transient membrane constrictions, or “pearling,” underlie the regular spacing of mitochondrial genomes Jelle van den Ameele1,2 and Julien Prudent1 Mitochondria are small, dynamic subcellular structures involved in many physiological functions, including energy production. They stand out among eukaryotic organelles because they have their own genome, a souvenir of their bacterial origin that remains essential for cellular energy metabolism. Mitochondrial DNA (mtDNA) is present in hundreds to thousands of copies per cell, assembled into nucleoprotein complexes called nucleoids. Nucleoids undergo continuous replication and turnover, are distributed regularly along the mitochondrial network, and usually contain only one or two mtDNA molecules (1). …
摘自《科学》(Science)第392卷 第6793期 · 2026年4月2日,J. van den Ameele and J. Prudent。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。