Modality-specific neurovascular coupling via layer-segregated arteriole networks · A. Malescot et al.
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Full article and list of author affiliations: https://doi.org/10.1126/science.aeb5077 Antoine Malescot, Milene R. Malheiros-Lima, Laurianne Zana, Michael C. Bennett, Éric Martineau, Franca Schmid, Ravi L. Rungta* INTRODUCTION: The brain continuously adjusts blood flow in response to elevations in neuronal activity through a process known as neurovascular coupling. These vascular responses form the basis of widely used brain imaging methods, such as functional magnetic resonance imaging (fMRI), which infer neuronal activity from local changes in blood oxygenation, flow, velocity, or volume. Although neurovascular signals are generally assumed to reflect neuronal activity in a consistent manner, different sensory experiences recruit distinct neural circuits across cortical layers. How these differences shape blood flow regulation within the brain remains poorly understood. …
摘自《科学》(Science)第393卷 第6813期 · 2026年8月20日,A. Malescot et al.。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。