原文开头
WHILE drugs for treating obesity such as semaglutide have been successful (see “Weight-loss drugs should get cheaper”, left), the hope is that the experimental treatments on trial soon will prove even more effective. In 2023, a drug called tirzepatide (sold as Mounjaro for diabetes) was also approved for weight loss, marketed as Zepbound. Tirzepatide improves on semaglutide by having a dual action: it mimics both GLP-1 and another hormone called GIP, which is involved in regulating energy use and storage. It has similar side effects to semaglutide. In a head-to-head trial, semaglutide reduced people’s weight by 14 per cent, on average, over 72 weeks, whereas tirzepatide lowered it by 20 per cent. …
摘自《新科学家》(New Scientist)第3576期 · 2026年1月3日。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。