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《新科学家》 第270卷 第3598期 · 2026年6月6日 · 中文解读

3D打印淋巴结或可扩大癌症治疗的可及性

3D-printed lymph nodes could widen access to cancer therapy · Carissa Wong
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本文报道了利用3D打印技术制造淋巴结样结构,以提高CAR T细胞生产效率并降低成本的研究。
原文开头
CAR T-cell therapy, when someone’s immune cells are genetically engineered to kill cancer cells, is highly effective for treating certain types of cancer, but it is too expensive to be widely available worldwide. But utilising 3D printing could mean that these engineered cells are produced for less money and – crucially – faster. This is usually done by mixing the cells with tiny beads that activate their proliferation. They are also mixed with a harmless virus that delivers them the genetic code for a protein that targets molecules on the surface of cancer cells, called a chimeric antigen receptor (CAR). Typically, 30 to 70 per cent of the T-cells are successfully reprogrammed, with a higher proportion tied to better outcomes. …
摘自《新科学家》(New Scientist)第270卷 第3598期 · 2026年6月6日,Carissa Wong。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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