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《科学》 第392卷 第6801期 · 2026年5月28日 · 中文解读

离体人脑用于药物测试

Disembodied human brains used for drug testing · Sara Reardon
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初创公司Bexorg通过恢复已故捐赠者全脑的部分功能,旨在更好地测试神经退行性疾病药物。
原文开头
As it metabolizes experimental drugs, sensors record the reactions, captur- ing hundreds of data points on its cells, proteins, and physiology. Then, after 24 hours in this state, it will be sliced into hundreds of pieces for more detailed study. er’s, or amyotrophic lateral sclerosis. Bexorg can biopsy the brains and dis- cover how long a drug stays in cells, whether it hits its molecular target, and any hints of side effects. Bexorg has largely stayed under the radar. Its founders have pub- lished no papers on its work other than initial experiments with pig brains, although Vrselja says they are preparing their first paper on human ones. Now, the company is scaling up and inviting new attention. …
摘自《科学》(Science)第392卷 第6801期 · 2026年5月28日,Sara Reardon。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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