单基因触发胚胎发育

A master switch has been discovered that turns on human embryonic development, a finding that could help improve IVF success rates, reports Michael Le Page WE NOW know the master gene that controls embryonic development in people. Called NANOG, its role has been identified by making precise changes to the DNA of fertilised eggs using a technique called CRISPR base editing. When NANOG is switched off (right), the embryo doesn’t develop LOKE CENTRE FOR TROPHOBLAST RESEARCH, UNIVERSITY OF CAMBRIDGE The discovery might lead to ways to boost the success rate of in vitro fertilisation (IVF), and help treat non-fertility-related conditions. …