神秘药物改善帕金森病小鼠症状

Treatments that target the glymphatic system, which removes problematic proteins from the brain, could be the key to treating Parkinson’s disease, finds Carissa Wong A MYSTERIOUS drug has improved the mobility and balance of mice with Parkinson’s-like symptoms. The drug works by boosting the brain’s waste disposal system to remove toxic protein clumps, but the researchers behind the work aren’t yet revealing what the treatment is, referring to it only as compound X. much more accurately than other models where symptoms are induced via brain damage, such as toxin exposure, without replicating the alpha-synuclein clumps we see in people, says Yan. She presented the study findings at the Oxford Glymphatic and Brain Clearance Symposium in the UK on 1 April. …