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《科学》 第392卷 第6802期 · 2026年6月4日 · 中文解读

记忆再激活驱动经验依赖性睡眠的适应性调节

Memory reactivation underlies experience-dependent adaptive regulation of sleep · K. Inokuchi
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这篇讲什么
该研究通过小鼠实验发现,睡眠期间记忆印迹的再激活会根据近期经历的情绪内容主动调节睡眠结构,负面记忆促进觉醒,正面记忆稳定睡眠,并揭示了其神经回路机制。
原文开头
Memory reactivation underlies experience- dependent adaptive regulation of sleep Full article and list of author affiliations: https://doi.org/10.1126/ science.aed8630 Menghan Yu, Junjie Wang†, Zihan Zhai†, Ruoyi Huang†, Guofan Fan, Xiaoya Su, Yijun Niu, Haochen Zhu, Jiayi Chen, Grace Jiang, Tian Zhang, Yi Zhong*, Bo Lei* INTRODUCTION: Sleep is not a static state but a dynamic process regulated by prior waking experiences. Memory replay or reactiva- tion during sleep plays a main role in memory consolidation and forgetting. However, whether memory activity itself shapes sleep physiology remains poorly understood. RATIONALE: The influences of daily experience on subsequent sleep have been widely observed across species. …
摘自《科学》(Science)第392卷 第6802期 · 2026年6月4日,K. Inokuchi。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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