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《科学》 第391卷 第6790期 · 2026年3月12日 · 中文解读

艾滋病治愈新策略:触发免疫警报清除病毒

HIV cure bid has virus trip immune alarm · J. Cohen
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本文报道了一种新的艾滋病治愈策略,通过触发CARD8免疫传感器来清除潜伏的HIV感染细胞,并在实验室和患者研究中显示出初步成效。
原文开头
Strategy produces promising results in cell studies and infected people JON COHEN, in Denver H IV research has led to a bounty of medicines that can control the infection and prevent immune de- struction for a lifetime. But a cure for the more than 40 million people liv- ing with HIV remains elusive. Treat- ments have only rid the virus from 11 people, and those successes took a stem cell transplant whose primary purpose was to treat a presumably unrelated blood cancer—an im- practical approach for routine use. The new cure strategy centers on one of the many internal sensors T cells and macrophages use to detect microbes. …
摘自《科学》(Science)第391卷 第6790期 · 2026年3月12日,J. Cohen。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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