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《科学》 第391卷 第6786期 · 2026年2月12日 · 中文解读

科学家揭示腺病毒载体新冠疫苗引发罕见血栓副作用的原因

Rare, dangerous side effects from COVID-19 vaccines explained · G. Vogel and K. Kupferschmidt
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研究人员发现,腺病毒载体新冠疫苗在极少数接种者中引发致命血栓和出血的机制,与抗体基因突变和腺病毒蛋白的相互作用有关。
原文开头
Scientists discover why adenovirus-based shots caused life-threatening blood clots and bleeding in some patients GRETCHEN VOGEL and KAI KUPFERSCHMIDT I n February 2021, soon after the first COVID-19 vaccines were rolled out in Europe, hemato- logist Sabine Eichinger of the Medical University of Vienna was confronted with a disturbing case: a 49-year-old nurse who had unusual blood clots and uncontrollable bleed- ing after receiving AstraZeneca’s vac- cine. The woman died, and Eichinger could not get the case out of her head. “I could barely sleep,” she says. Beyond the woman’s personal tragedy, Eichinger worried what it might mean for the lifesaving vaccine. …
摘自《科学》(Science)第391卷 第6786期 · 2026年2月12日,G. Vogel and K. Kupferschmidt。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。
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