《科学》 第391卷 第6787期 · 2026年2月19日 · 中文解读
赛博格胰岛类器官
Cyborg pancreatic islet organoids · J. Lang and M. Raoux
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本文介绍了李等人开发的一种包含微电极的人类多能干细胞来源的胰岛类器官,能够实现长期、非侵入性的电生理监测和基因表达分析,为糖尿病研究和细胞治疗提供了新工具。
原文开头
Bio-nanoelectronic islets are new tools for diabetes research and therapy Jochen Lang and Matthieu Raoux S tem cells can be manipulated to form organoids— three-dimensional structures that mimic the vi- tal functions of organs. Organoids are useful for research into developmental, physiological, and pathophysiological mechanisms, and for improv- ing therapies. The ability to monitor and steer organoid maturation in situ, noninvasively, in real time, and over months has the potential to transform biomedical re- search and regenerative medicine but poses considerable biotechnological challenges (1). On page 786 of this issue, Li et al. (2) report the differentiation of human pluripotent stem cells into pancreatic islet micro-organs containing microelectrodes. …
摘自《科学》(Science)第391卷 第6787期 · 2026年2月19日,J. Lang and M. Raoux。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。

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