《新科学家》 2026年10月10日 · 中文解读
新发现的脑细胞可能是妊娠成功的关键
Newly found brain cells may be key for pregnancy success · Alice Klein
约 4 分钟Neuroscience在小程序里点播,20 到 60 分钟做好
这篇讲什么
美国斯坦福大学的Nirao Shah团队在小鼠大脑深处一个名为视前下丘脑的微小区域发现了一类此前未知的神经元,它们只在妊娠期出现,基因表达水平变化超过30倍。这些神经元似乎负责协调胚胎在子宫内着床并维持妊娠,缺失它们的雌鼠虽能怀孕,但妊娠都在早期终止。研究团队还在人类女性大脑中发现了同样的神经元,这或许能为不明原因的反复流产和试管婴儿困难提供线索。
原文开头
A TINY region deep inside the brain is fundamental to viable pregnancies in mice. These neurons are also present in human female brains and could provide clues about unexplained recurrent miscarriages and IVF difficulties. Nirao Shah at Stanford University, California, and his colleagues discovered the neurons while looking for gene expression changes in different parts of the female mouse brain during pregnancy. They observed a small population of neurons that completely transformed. The levels of gene expression in these neurons changed over 30-fold when mice became pregnant for the first time, converting them to a new class of neurons that functioned in a completely different way by mid-gestation. “This cell type is exclusive to pregnancy,” the researchers write. …
摘自《新科学家》(New Scientist)2026年10月10日,Alice Klein。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。

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