Massively Parallel Sequencing Technology Allows Forensic Biologists to Tackle Cold Cases · Rebecca Roberts, PhD
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Advances in DNA sequencing technology help forensic biologists identify suspects where traditional DNA profiling has failed, including decades-old unsolved crimes. BY REBECCA ROBERTS, PhD I t was the afternoon of April 24, 2018, when Sacramento police made the mon- umental arrest of 72-year-old Joseph DeAngelo, widely known as the Golden State Killer. DeAngelo was a notorious burglar, rapist, and serial murderer who had eluded them for decades. It was massively parallel sequencing (MPS), otherwise known as next-gener- ation sequencing, that enabled detec- tives to identify DeAngelo based on a DNA profile match on a public ances- try database and arrest him for his pro- lific crimes. …
摘自《科学家》(The Scientist)第40卷 第2期 · 2026年夏季刊,Rebecca Roberts, PhD。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。