Parallel independent voltage computing along dendrites of CA3 pyramidal neurons · A. Noguchi et al.
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NeUROPhYsiOlOGY Parallel independent voltage computing along dendrites of CA3 pyramidal neurons Asako Noguchi1,2*†, Satoshi Terada1,2*†, George N. Zakka2, Cliodhna O’Toole2, Luke Reynolds2, Michelle Ann Land3, Balázs J. Rózsa4,5,6, François St- Pierre3,7,8, Attila Losonczy1,2,9* Dendritic computation contributes to information processing in cortical circuits. Hippocampal CA3 plays a central role in navigation, but how the dendrites of CA3 pyramidal neurons process information in vivo remains largely unknown. using voltage imaging across dendrites and somata of CA3 pyramidal neurons during virtual reality–guided navigation in mice, we found that the dendritic arbor comprises multiple independent computational units that can dynamically couple to or dissociate from somatic activity, depending on behavioral conditions. …
摘自《科学》(Science)第393卷 第6808期 · 2026年7月16日,A. Noguchi et al.。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。