A 5500-year-old Treponema pallidum genome from Sabana de Bogotá, Colombia · D. Bozzi et al.
原文开头
Davide Bozzi¹,²†, Nasreen Z. Broomandkhoshbacht³†, Miguel Delgado⁴,⁵,⁶†, Jane E. Buikstra⁷, Carlos Eduardo G. Amorim⁷,⁸, Kalina Kassadjikova³, Melissa Pratt Estrada⁹, Gilbert Greub¹⁰,¹¹, Nicolas Rascovan¹², David Šmajs¹³, Lars Fehren-Schmitz³,¹⁴*, Anna-Sapfo Malaspinas¹,²*, Elizabeth A. Nelson³,¹²,¹⁵* Treponematosis, a bacterial infection caused by Treponema pallidum subspecies and T. carateum (yaws, bejel, syphilis, pinta), has afflicted humans for millennia. Despite paleopathological evidence and emerging genomic data, little is known about the evolutionary history of these pathogens. We report a 5500-year-old Treponema genome (TE1-3) from Middle Holocene hunter-gatherer contexts of the rock shelter Tequendama I in Colombia. Our analyses place TE1-3 as a sister lineage to all known T. …
摘自《科学》(Science)第391卷 第6783期 · 2026年1月22日,D. Bozzi et al.。仅引用开头一小段供了解文章,版权归原刊所有,全文请阅读原刊。